Which is an integral membrane protein that forms the tetramer and facilitates the diffusion of water and some small, unmodified solutes across cellular membranes?

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SSC CPO 2024 Official Paper-I (Held On: 27 Jun, 2024 Shift 3)
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  1. Immunoglobulins
  2. Aquaporins
  3. Mucins
  4. Transferrin

Answer (Detailed Solution Below)

Option 2 : Aquaporins
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The correct answer is Aquaporins

Key Points

  • Aquaporins are integral membrane proteins that form tetramers in the cell membrane.
  • They facilitate the diffusion of water and some small, unmodified solutes across cellular membranes.
  • They play a crucial role in the regulation of water balance in various tissues and organs.
  • Aquaporins are found in a variety of organisms, including animals, plants, and microorganisms.

Additional Information

  • The discovery of aquaporins was awarded the Nobel Prize in Chemistry in 2003 to Peter Agre.
  • Aquaporins are also involved in various physiological processes such as kidney function, brain water homeostasis, and plant water transport.
  • There are several types of aquaporins, each with specific functions and regulatory mechanisms.
  • Mutations or malfunctions in aquaporins can lead to various medical conditions, including diabetes insipidus and brain edema.
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