The hybridoma technique was developed by whom?

This question was previously asked in
UKPSC Combined Upper PCS (Prelims) Exam (General Studies) Official Paper-I (Held On: 14 Jul, 2024)
View all UKPSC Combined Upper Subordinate Service Papers >
  1. Louis Pasteur
  2. George Kohler and César Milstein.
  3. Edward Jenner
  4. Burnet

Answer (Detailed Solution Below)

Option 2 : George Kohler and César Milstein.
Free
UPSC PYP Prelims Snippet
8.4 K Users
30 Questions 60 Marks 35 Mins

Detailed Solution

Download Solution PDF

The correct answer is option 2.

Key Points

  • The hybridoma technique was developed by George Köhler and César Milstein in 1975. Hence, option 2 is correct.
  • It is used to produce monoclonal antibodies by fusing a specific antibody-producing B-cell with a myeloma (cancer) cell, creating a hybrid cell (hybridoma).
  • This hybridoma can proliferate indefinitely and produce large quantities of identical (monoclonal) antibodies.
  • They received the Nobel Prize in Physiology or Medicine in 1984 for this groundbreaking discovery.
  • Other Options:
    • Louis Pasteur: Pioneer in microbiology and vaccination.
    • Edward Jenner: Developed the first successful smallpox vaccine.
    • Sir Frank Macfarlane Burnet: Known for clonal selection theory in immunology.
Latest UKPSC Combined Upper Subordinate Service Updates

Last updated on Jul 4, 2025

-> UKPSC Upper PCS Prelims Admit Card is released on 18 June.

-> UKPSC Upper PCS Answer Key 2025 has been released 

-> UKPSC Combined Upper Subordinate Services Prelims Exam will be held on 29 June.

-> UKPSC Combined Upper Subordinate Services notification has been released for 123 posts on 7th May 2025.

-> Candidates can submit their online applications till 27th May 2025. Application correction window will accept the changes from 3rd June to 12th June 2025.

-> UKPSC Combined Upper Subordinate Service prelims exam date will soon be announced. The admit card link will be live too on the official website.

-> The selection process includes Prelims, Mains and Interview stages.

-> This is a great Uttarakhand Government Job opportunity. Prepare for the exam with UKPSC Combined Upper Subordinate Service Previous Year Papers.

Get Free Access Now
Hot Links: teen patti master app real teen patti teen patti chart teen patti noble