The Adenosine deaminase deficiency results into

  1. Addison's disease
  2. Dysfunction of Immune system
  3. Parkinson's disease
  4. Digestive disorder

Answer (Detailed Solution Below)

Option 2 : Dysfunction of Immune system
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Correct answer: 2)

Concept:

  • When DNA is broken down, it forms deoxyadenosine which is toxic to our lymphocytes.
  • Adenosine deaminase is an enzyme that removes deoxyadenosine and converts it into deoxyinosine, which is not harmful.

Explanation:

  • Option 1: Addison’s disease is caused due to hyposecretion of cortisol or aldosterone from the adrenal glands.
  • Option 2:
  • Dysfunction of the immune system is caused by adenosine deaminase enzyme deficiency.
  • It causes a disease known as severe combined immunodeficiency (SCID).
  • An individual loses its immunity against all bacteria, viruses, and fungi.
  • Option 3:
  • Parkinson’s disease is a disorder of the nervous system that is caused due to very low dopamine levels.
  • Nerve cells are damaged, and people will often suffer from tremors.
  • Option 4:
  • The digestive disorder is a disorder that affects the alimentary canal from the mouth to the anus.
  • Celiac disease, irritable bowel syndrome, and acid reflux are all examples of digestive disorders.

So, the correct answer is option 2.

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