Question
Download Solution PDFHistones are enriched with -
Answer (Detailed Solution Below)
Detailed Solution
Download Solution PDFThe correct answer is Lysine & Arginine
Expanation:
- The nucleosome is the basic structural unit of chromatin in eukaryotic cells. It plays a critical role in the packaging of DNA into a compact, dense shape, which allows for efficient storage and regulation of genetic information.
- A nucleosome consists of a segment of DNA wound around a core of histone proteins.
- Histones are rich in the basic amino acid residues lysine and arginine. Both the amino acid residues carry positive charges in their side chains.
- Histones are organised to form a unit of eight molecules called histone octamer.
- The histone core around which DNA is wrapped is composed of eight histone molecules: two each of histone proteins H2A, H2B, H3, and H4.
- The negatively charged DNA is wrapped around the positively charged histone octamer to form a structure called nucleosome
- A typical nucleosome contains 200 bp of DNA helix.
Last updated on Jun 16, 2025
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