Clemmensen reduction of a ketone is carried out in the presence of:

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  1. LiAlH4
  2. Zn-Hg with HCI
  3. Glycol with KOH
  4. H2 with Pt as catalyst

Answer (Detailed Solution Below)

Option 2 : Zn-Hg with HCI
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CONCEPT:

Clemmensen Reduction

  • Clemmensen reduction is a chemical reaction used to reduce ketones to the corresponding alkanes.
  • It involves the use of zinc amalgam (Zn-Hg) and hydrochloric acid (HCl).
  • The mechanism proceeds through the formation of a zinc intermediate that facilitates the reduction.

EXPLANATION:

example-of-clemmensen-reduction-bb6c77eb

  • In Clemmensen reduction, the conditions required are acidic and involve the use of metal catalysts.
  • The reduction of the ketone occurs in the presence of Zn-Hg and HCl, which provides the necessary electrons for the reduction process.
  • Therefore, the correct answer is option 2: Zn-Hg with HCl.

Therefore, Clemmensen reduction of a ketone is carried out in the presence of Zn-Hg with HCl.

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