The synthetic equivalent of the given synthon is

F2 Madhuri Teaching 10.01.2023 D7

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CSIR-UGC (NET) Chemical Science: Held on (26 Nov 2020)
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  1. t-butyl isocyanide
  2. t-butyl cyanide
  3. t-butyl cyanate
  4. t-butyl isocyanate

Answer (Detailed Solution Below)

Option 1 : t-butyl isocyanide
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Concept:

Synthetic Equivalent and Synthon:

  • A reagent carrying out the function of a synthon, which cannot itself be used, often because it is too unstable.
  • A reagent or generalized fragment, usually an ion produced by dissociation of a synthetic equivalent.

Explanation:

  • t-butyl isocyanide is a type of alkyl isocyanide.
  • Isocyanides can act as a nucleophile as well as electrophile through the same C atom.
  • The adduct forms from the alkyl isocyanide at the alpha-C atom concludes the synthetic equivalent of the given synthon is t-butyl isocyanide.

F2 Madhuri Teaching 10.01.2023 D8

Conclusion:

Hence, the synthetic equivalent of the given synthon is t-butyl isocyanide.

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