How many Carbon atoms are present in a Pyruvate molecule ?

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UPSC CDS-I 2025 (General Studies) Official Paper (Held On: 13 Apr, 2025)
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  1. 2
  2. 3
  3. 4
  4. 5

Answer (Detailed Solution Below)

Option 2 : 3
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The correct answer is 3.

Key Points

  • A pyruvate molecule contains 3 carbon atoms, forming the basic structure of this compound.
  • It is the end product of glycolysis, a key metabolic pathway in cellular respiration.
  • During glycolysis, one molecule of glucose (6 carbon atoms) is broken down into two molecules of pyruvate, each containing 3 carbon atoms.
  • Pyruvate can undergo further metabolic processes such as conversion to acetyl-CoA or fermentation depending on oxygen availability.
  • The chemical formula of pyruvate is C3H4O3, confirming the presence of 3 carbon atoms in its structure.

Additional Information

  • Glycolysis:
    • Glycolysis is the metabolic pathway that converts glucose into pyruvate, producing ATP and NADH in the process.
    • This pathway occurs in the cytoplasm of cells and does not require oxygen, making it an anaerobic process.
    • Glycolysis consists of 10 enzymatic steps and is a fundamental part of cellular respiration.
  • Pyruvate Decarboxylation:
    • In the presence of oxygen, pyruvate is converted into acetyl-CoA in the mitochondria, a process essential for the Krebs cycle.
    • This step produces NADH and releases carbon dioxide.
  • Fermentation:
    • Under anaerobic conditions, pyruvate can undergo fermentation to produce lactate in animals or ethanol and carbon dioxide in yeast.
    • Fermentation regenerates NAD+, allowing glycolysis to continue in the absence of oxygen.
  • Importance of Pyruvate:
    • Pyruvate is a central metabolite and acts as a key junction in various metabolic pathways.
    • It connects anaerobic glycolysis to aerobic respiration and fermentation.
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