With the help of given pedigree, find out the probability for the birth of a child having no disease and being a carrier (has the disease mutation in one allele of the gene) in F3 generation. 
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NEET 2025 Official Paper (Held On: 04 May, 2025)
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  1. 1/4 
  2. 1/2
  3. 1/8
  4. Zero 

Answer (Detailed Solution Below)

Option 1 : 1/4 
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Detailed Solution

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The correct answer is 1/4

Explanation:

  • A pedigree chart is a diagram that shows the occurrence and appearance of phenotypes of a particular gene or organism and its ancestors, often used to determine inheritance patterns.
  • Carriers are individuals who have one recessive allele (disease mutation) and one normal allele. They do not show symptoms of the disease but can pass the mutation to their offspring.

X-linked Recessive Mutation:

  • Typically, X-linked recessive traits are more common in males because they only have one X chromosome.
  • Affected males pass the trait to all their daughters, who are carriers, and to none of their sons.
  • Carrier females (having one normal and one affected X chromosome) can pass the trait to both sons and daughters.

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Thus, the correct answer is 1/4 (XXc)

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