Incorrect statement about metaphase stage.

The correct answer is Centromere division

Explanation:

Metaphase is a stage of mitosis in the eukaryotic cell cycle where chromosomes align in the middle of the cell before being separated into each of the two daughter cells. During metaphase, the chromosomes become highly condensed, making them easier to observe under a microscope.

• Spindle fibers are attached to small disc-shaped structures at the surface of centromeres called kinetochores: This is a correct statement. During metaphase, the spindle fibers attach to the kinetochores, which are protein complexes assembled on the centromere of each chromosome.
• The plane of alignment of the homologous pair of chromosomes at metaphase is referred to as the metaphase plate: This is a correct statement. The metaphase plate is an imaginary plane that is equidistant from the two centrosome poles and is where chromosomes align during metaphase.
• Chromosomes appear to be made up of two sister chromatids: This is a correct statement. Each chromosome during metaphase consists of two sister chromatids, which are identical copies of the original chromosome, connected by a centromere.
• Centromere division: This is the incorrect statement. Centromere division, or the separation of sister chromatids, occurs during anaphase, not during metaphase. During metaphase, the chromosomes are merely aligned at the metaphase plate.