In which year did E Gorter and F Grendel make a breakthrough by examining the surface area of lipids and concluded that the lipid surface surrounding cells must be of two layers?  

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SSC CGL 2023 Tier-I Official Paper (Held On: 19 Jul 2023 Shift 1)
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  1. 1910
  2. 1925
  3. 1945
  4. 1962

Answer (Detailed Solution Below)

Option 2 : 1925
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The correct answer is 1925.

Key Points

  • Langmuir Trough Experiment:-
    • E Gorter and F Grendel made a breakthrough by examining the surface area of lipids and concluded that the lipid surface surrounding cells must be of two layers in the year 1925.
    • Their experiment involved extracting lipids from red blood cells and then spreading them out on a water surface to form a monolayer.
    • They then measured the area of the monolayer and found that it was twice the area of the surface area of the red blood cells.
    • This led them to conclude that the lipid bilayer model of the cell membrane must be correct.
    • Gorter and Grendel's work was a major breakthrough in the understanding of cell structure and function.
    • It helped to establish the lipid bilayer model of the cell membrane, which is still the accepted model today.

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